منابع مشابه
Gene duplication and evolution.
Lynch and Conery (1) presented one of the first serious efforts to study the evolutionary fate of gene duplication using genomic sequence data. Their analysis led to several interesting observations, particularly with respect to the rate of gene duplication in eukaryotic genomes and the subsequent halflife of duplicates. These two parameters are of particular importance in studying the evolutio...
متن کاملSimulating evolution by gene duplication.
By considering the recent finding that unequal crossing over and other molecular interactions are contributing to the evolution of multigene families, a model of the origin of repetitive genes was studied by Monte Carlo simulations. Starting from a single gene copy, how genetic systems evolve was examined under unequal crossing over, random drift and natural selection. Both beneficial and deter...
متن کاملEvolution of ribonuclease inhibitor by exon duplication.
The leucine-rich repeat (LRR) is a prevalent structural motif that mediates specific protein-protein interactions (Kobe and Deisenhofer 1995b). The LRR is defined by a region of 20–29 residues that contains the consensus sequence: XLXXLXLXXN, where L, N, and X are leucine, asparagine, and any residue, respectively. Typically, LRRs are displayed in 1–30 tandem copies within a protein. The first ...
متن کاملEvolution by gene duplication: an update
The importance of gene duplication in supplying raw genetic material to biological evolution has been recognized since the 1930s. Recent genomic sequence data provide substantial evidence for the abundance of duplicated genes in all organisms surveyed. But how do newly duplicated genes survive and acquire novel functions, and what role does gene duplication play in the evolution of genomes and ...
متن کاملEvolution of Gene Duplication in Plants1[OPEN]
Ancient duplication events and a high rate of retention of extant pairs of duplicate genes have contributed to an abundance of duplicate genes in plant genomes. These duplicates have contributed to the evolution of novel functions, such as the production of floral structures, induction of disease resistance, and adaptation to stress. Additionally, recent whole-genome duplications that have occu...
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ژورنال
عنوان ژورنال: Genome Biology
سال: 2000
ISSN: 1465-6906
DOI: 10.1186/gb-spotlight-20000906-02